<< 11th Edition. 4th ed. <> Occup. x3R235W(2300P@& Hazards What is this information? 1296. In one instance mixing 40 cc of bromine and 150 cc of dimethyl formamide resulted in an increase of temperature to above 100 deg C and an increase in pressure to above 2000 psi. Molecular Weight 73.09. Fire Hazard Dimethylformamide (DMF) 68-12-2 200-679-5 100% HAZARD CLASSIFICATION: T. RISK PHRASES: R20-21, R36, R60. Boston, MA: Butterworth-Heinemann Ltd., 1990. Bretherick, L. Handbook of Reactive Chemical Hazards. When mixed with air in certain proportions, vapor is flammable. 332. May cause respiratory tract irritation. Manufactured, packaged and stored under current Good Manufacturing Practices (cGMP) per 21CFR part 211 in FDA registered and inspected facilities stream A mixture of sodium hydride and dimethylformamide was heated to, and held at 50 deg C. An exothermic reaction, which increased the temperature to 75 deg C, could not be controlled by external cooling and the pilot-scale reactor contents erupted. First-aid measures Eye Contact Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes. Boston, MA: Butterworth-Heinemann Ltd., 1990. Dimetilformamida o composto orgnico com a frmula ( CH 3) 2 NC (O)H. Comumente abreviada como DMF (embora este acrnimo seja algumas vezes usado para dimetilfurano ), este lquido incolor miscvel com gua e a maioria dos lquidos orgnicos. Mutagenic for bacteria and /or yeast. <> Lithium azide and DMF are stable at 25 deg C during preparation of tert-alkyl azides, above 200 deg C the mixtures are shock-sensitive and highly explosive. First-aid measures _____ Page 2 / 8 N,N-Dimethylformamide Revision Date 03-Apr-2014 <> endstream 10th ed. 58 / Monday, March 26, 2012 / Rules and Regulations 06/17/2015 EN (English US) 3/9 5.2. Up to 100 ppm: (APF = 10) Any supplied-air respirator*, Up to 250 ppm: (APF = 25) Any supplied-air respirator operated in a continuous-flow mode*, Up to 500 ppm: (APF = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode*(APF = 50) Any self-contained breathing apparatus with a full facepiece(APF = 50) Any supplied-air respirator with a full facepiece, Emergency or planned entry into unknown concentrations or IDLH conditions: (APF = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode(APF = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus, Escape: (APF = 50) Any air-purifying, full-facepiece respirator (gas mask) with a chin-style, front- or back-mounted organic vapor canisterAny appropriate escape-type, self-contained breathing apparatus, Important additional information about respirator selection, Dimethyl formamide, N,N-Dimethylformamide, DMF. Commonly abbreviated as DMF, this colourless liquid is miscible with water and the majority of organic liquids. NN-Dimethylformamide-Anhydrous-Septum-Sealed-Bottle-DriSolvR at Spectrum Chemical. Due attention should also be given to the appropriate precautions necessary for handling chemicals. Hazard Class: 3: Package Group: III: UN ID: UN2265: Remove Product. It is a polar inert solvent. Compare Clear All. . (NFPA, 2010) General Description A water-white liquid with a faint fishy odor. <> May irritate eyes. Dimethylformamide ALSO CALLED 114057-15-7, 15175-63-0, 15175-77-6, 200-679-5, 33513-42-7, Dimethyl formamide, Dimethylamid kyselin. Dimethyl formamide and triethyl aluminum form explosive mixture when heated together. endobj Saving Lives, Protecting People, The National Institute for Occupational Safety and Health (NIOSH), National Institute for Occupational Safety and Health, A NIOSH Potential Occupational Carcinogens, B Thirteen OSHA-Regulated Carcinogens, D Substances with No Established RELs, E OSHA Respirator Requirements for Selected Chemicals, G 1989 Air Contaminants Update Project: Exposure Limits NOT in Effect, Type C & CE Definitions for Type C and Type CE Respirators, U.S. Department of Health & Human Services. Hazardous Ingredients: CAS # EC # ICSC # WT % Hazard Symbol; Risk Phrases Dimethylformamide (DMF) 68-12 2 200 679 5 1 0% HAZARD CLASSIFICATION: T RISK PHRASES: R20-21, R36, R60 NOTE: ALL WHMIS required information is included in appropriate sections based on the ANSI Z400.1-2004 format. Potential cancer hazard. by IARC. 2010-168 (2010). 1326. The investigation indicated that there was a highly exothermic reaction between dimethyl formamide and bromine. Vigorous reaction with alkylaluminums. Bretherick, L. Handbook of Reactive Chemical Hazards. Eval. :INr+|n:v{ f%2$Idbq1W;F94 qDk[g92+VaK%S{-/Gpo?X Causes respiratory tract irritation. Hazard(s) identification Classification This chemical is considered hazardous by the 2012 OSHA Hazard Communication Standard (29 CFR 1910.1200) Label Elements Signal Word Danger Hazard Statements Flammable liquid and vapor Causes serious eye irritation May damage the unborn child Harmful in contact with skin or if inhaled Company MILLIPLEX MAP Human Adipokine Magnetic Bead Panel 1 - Endocrine Multiplex Assay (HADK1MAG-61K) 1. 1.2: 9 h / 90 C / Inert atmosphere. >> endobj Avoidance of holding mixtures hot is recommended, particularly when scaling up reactions. Hazards not otherwise classified (HNOC) Lachrymator (substance which increases the flow of tears) 3. Dimethyl formamide and hexachlorobenzene react violently above 65 deg C. National Fire Protection Association; Fire Protection Guide to Hazardous Materials. Performance & security by Cloudflare. t1H@aL*9K?$B%_!+ Dimethylformamide is the organic compound with the formula (CH 3) 2 NC(O)H. Commonly abbreviated DMF, this colourless liquid is miscible with water and majority of organic liquids. Special hazards arising from the substance or mixture Fire hazard : DIRECT FIRE HAZARD. DMF is also used as carrier for inks and dyes in various printing and fiber-dying applications. <> Sittig's Handbook of Toxic and Hazardous Chemical Carcinogens 5th Edition Volume 1: A-H,Volume 2: I-Z. Molecular Formula C 3 H 7 NO. S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. endobj Ignition on contact with chromium trioxide. Additional troubleshooting resources. . 4th ed. Cleveland: CRC Press Inc., 1968. Bretherick, L. Handbook of Reactive Chemical Hazards. x3R235W(2300P@& /Producer(Sub Systems, Inc.)/CreationDate(D:20211227101701+05'00')/ModDate(D:20211227101701+05'00')/Creator(Sub Systems, Inc.) DMF is a common solvent for chemical reactions. Product Name N,N-Dimethylformamide. Bretherick, L. Handbook of Reactive Chemical Hazards. endstream 19 0 obj Boston, MA: Butterworth-Heinemann Ltd., 1990. Wiley-Interscience, Wiley & Sons, Inc. Hoboken, NJ. Vapors heavier than air. 21 0 obj This product has been classified in 4 0 obj Contact China Manufactory Haoayou New Material Technology Co., LTD for the product N-Dimethylformamide 99% liquid cas 68-12-2 Haoayou. MUTAGENIC EFFECTS: Mutagenic for mammalian somatic cells. Click to reveal The 1:1 adduct initially formed decomposes above 60 deg C with evolution of carbon dioxide and formation of a dimeric unsaturated quaternary ammonium salt. Cailin Delaney, Stephanie Smith, Philip Eskew, Cindy Silvester, Leigh Jason, and Samuel A. Abrash, "Photochemistry of HI-Allene Complexes in Argon Matrices", Poster Presented, Gordon Conference on Physics and Chemistry of Weakly Bound Complexes, Bates College, Lewiston, Maine, July 20-25, 2003. Rinse skin with water or shower. Vigorous exothermic reaction with magnesium nitrate, sodium + heat, sodium hydride + heat, sulfinyl chloride + traces of iron or zinc, 2,4,6-trichloro-1,3,5-triazine. Flash point 136F. x3R235W(2300P@& The global market is . /Length 4942 >> Availability of Hazard Identification Materials for N,N-Dimethylformamide and . %PDF-1.4 <> Get medical attention immediately if symptoms occur. stream 6 0 obj Cloudflare monitors for these errors and automatically investigates the cause. 10 0 obj Water soluble. ACGIH A4: Not classifiable as a human carcinogen (N, N-dimethylformamide). at or above 100F and below 140F. The Royal Society of Chemistry. Cyanuric chloride reacts vigorously and exothermically with DMF after a deceptively long induction period. Carbon tetrachloride; other halogenated compounds when in contact with iron; strong oxidizers; alkyl aluminums; inorganic nitrates, inhalation, skin absorption, ingestion, skin and/or eye contact, irritation eyes, skin, respiratory system; nausea, vomiting, colic; liver damage, enlarged liver; high blood pressure; face flush; dermatitis; In Animals: kidney, heart damage, Eyes, skin, respiratory system, liver, kidneys, cardiovascular system, Centers for Disease Control and Prevention. Chat now for more business. Features of dimethylformamide: Highly purified and tested to ensure reliable performance in HPLC, mass spectrometry and sequencing applications Packaged in solvent-rinsed amber glass bottles and sealed with PTFE-lined fluorocarbon caps General properties of DMF Alternative names: N,N-Dimethylformamide, N-Formyldimethylamine IVN-RAT LD50 2000 mg kg-1, IPR-RBT LD50 1000 mg kg-1 OU Chemical Safety Data (No longer updated) More details: Safety: 3 Alfa Aesar 13808, 22915, 39117, 41859, 43465, 43997, A13547: Hazard classification & labelling Hazard classification and labelling The 'Hazard classification and labelling' section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. Boston, MA: Butterworth-Heinemann Ltd., 1990. Dimethylformamide. Chemicals Listed Effective October 27, 2017 as Known to the State of California to Cause Cancer: N,N-Dimethylformamide, 2-Mercaptobenzothiazole, and Tetrabromobisphenol A. November 5, 2008 Meeting of The Science Advisory Board's Carcinogen Identification Committee. x3R235W(2300P@& Dimethylformamide Important Raw Materials and Intermediates. Lefaux, R. Practical Toxicology of Plastics. To help support the investigation, you can pull the corresponding error log from your web server and submit it our support team. Bretherick, L. Handbook of Reactive Chemical Hazards. Please include the Ray ID (which is at the bottom of this error page). 1 0 obj endobj 15 0 obj New editions through 13th ed. This substance has caused adverse reproductive and fetal effects in animals. Hazard Symbols: C - Corrosive: Risk Codes: R34 - Causes burns R37 - Irritating to the respiratory system R14 - Reacts violently with water: Safety Description: S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. f Exposure to Dimethylformamide can cause headache, dizziness, nausea and vomiting. Material Safety Data Sheet N,N-Dimethylformamide, 99% ACC# 95221 MSDS Name: N,N -Dimethylformamide, 99% . There is an issue between Cloudflare's cache and your origin web server. <> {{A0`[1. 4th ed. t1H@aL*9K?$R%_!+ Hazardous Ingredients: CAS # EC # ICSC # WT % Hazard Symbol; Risk Phrases. Class II Combustible Liquid: Fl.P. To help support the investigation, you can pull the corresponding error log from your web server and submit it our support team. )j&Qm8e_)G MJm6)q67ZihR~Qbm72)(Ugt{r uu&cGsN'01Fotct4bH&}y"=VyoZ{Y8Lof~aW!E6ig7_AtF!Fa|q>j=Op@~oD>t'd41dhdmB Boston, MA: Butterworth-Heinemann Ltd., 1990. t1H@aL*9K?$D%_!+ May cause central nervous system effects. (Select up to 3 total.) Bretherick, L. Handbook of Reactive Chemical Hazards. Get the latest public health information from CDC: https://www.coronavirus.govGet the latest research information from NIH: https://www.nih.gov/coronavirus, PDF documents can be viewed with the free Adobe Reader. Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. This may have arisen either from interaction of the dichloro cmpd with the solvent or from the known instability of hot solutions of the tetrahydroborate in DMF. stream Lachrymator (substance which increases the flow of tears). May cause liver and kidney damage. All other countries, please order HTH17MAG-14K. u:!DI4eBIa4%\0IYp)fj;]A 6p>htr*IyW KZncm# ll>#Jvnyg$/ sn{gW?%/;o}#XyKo>;{oy7Rn.9kK{_|}'_;{~yeZ?zOxD|/o|qO75|s|Cy]ao_|_y_|so>.oL^sf//?}g\n_}\'_}WYc/.9ySo@?u>u?65. (N,N-Dimethylformamide) Specifictarget organ toxicity- single exposure No data available(N,N-Dimethylformamide) Specifictarget organ toxicity- repeated exposure Toxic by inhalation or skin absorption. cas: 68-12-2 molecular formula: c3h7no molecular weight (g/mol): 73.10 mdl number: mfcd00003284 inchi key: zmxddkwlczadiw-uhfffaoysa-n synonym: dimethyl formamide, dimethylformamid, dimethylformamide, dimetilformamide, dmf, dmfa, dwumetyloformamid, formamide, n,n-dimethyl, n,n-dimethylmethanamide, n-formyldimethylamine pubchem cid: 6228 chebi: <> NIOSH Pocket Guide to Chemical Hazards. <> Compare Clear All. DMF is a common solvent for chemical reactions. )_ [ S 9!jC %(~Dpd,B|IY1 GNJ8`4RX@#pl!\7#piQF(DNuNWMLH3 . The store will not work correctly in the case when cookies are disabled. Enable or disable the translated content using this setting. If breathing is difficult, give oxygen. Med. N,N-Dimethylformamide MSDS - 103034 - Merck. To effect reduction to the parent heterocycle, a solution of 2,5-bis-endo-dichloro-7-thiabicyclo(2.2.1)heptane in DMF was being added to a hot solution of sodium tetrahydroborate in the same solvent, when a violent explosion occurred. 185.212.128.106 5 0 obj <> 996. Boston, MA: Butterworth-Heinemann Ltd., 1990. Slightly less dense than water. CAS No. oqdN#" It can also . Health effects / safety hazards: Dimtehylformamide is extremely dangerous and toxic by ingestion. Bretherick, L. Handbook of Reactive Chemical Hazards. WHO; Environ Health Criteria 114: Dimethylformamide p.17 (1991). Molecular Weight 73.1 Boiling Point 307F Freezing Point -78F Solubility Miscible Vapor Pressure 3 mmHg Ionization Potential 9.12 eV Specific Gravity 0.95 Flash Point 136F Upper Explosive Limit 15.2% Lower Explosive Limit (212F): 2.2% Harmful if absorbed through skin or if inhaled. 8 0 obj Description: Emplura* N, N-Dimethylformamide, Cas number: 68-12-2, Chemical Formula:HCON(CH3)2, Solvent for lab application, 1l. x3R235W(*T0PR0T(Y@@QC= P AJ 1TpW 491-76. Addition of 2 g chromium trioxide to 18 mL of solvent to form a 10% wt solution caused immediate ignition and ejection of the flask contents. Occupational Safety and Health Administration 200 Constitution Ave NW Washington, DC 20210 800-321-6742 (OSHA) TTY www.OSHA.gov . Acute (short-term) exposure to dimethylformamide has been observed to damage the liver in animals and in humans. Association of Official Analytical Chemists. DMF dimethylformamide | C6H14N2O2 | CID 17824068 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. 116. 4th ed. X`I%&/m{JJt`$@iG#)*eVe]f@{{;N'?\fdlJ!?~|? Dimethylformamide (2) Dimethylformamide Synonyms: N,N-Dimethylformamide, DMF, NSC 5356 Linear Formula: HCON (CH3)2 CAS Number: 68-12-2 Molecular Weight: 73.09 EC Number: 200-679-5 Product Comparison Guide Use the product attributes below to configure the comparison table. Cloudflare Ray ID: 76a1b05d3a460b4b Orders subjected to minimum order quantity. Boston, MA: Butterworth-Heinemann Ltd., 1990. 18 0 obj Lewis, R.J. Sr. (ed) Sax's Dangerous Properties of Industrial Materials. f Inhaling Dimethylformamide can irritate the nose and throat causing coughing and wheezing. stream endstream Safety Data Sheet for N,N-Dimethylformamide 100397. . <> endobj 1372. : 68-12-2 Formula: C3h7no EINECS: 200-679-5 Type: Synthesis Material Intermediates Appearance: Liquid Quality: Industrial Product Description Dimethylformamide DMF is a clear, colorless, hygroscopic liquid with a slight amine odor. Please include the Ray ID (which is at the bottom of this error page). Department of Health & Human Services, Centers for Disease Control & Prevention. Categories Aliphatic Nitrogen Compounds. Symptoms of acute exposure in humans include abdominal pain, nausea, 2004. 3rd ed. <> Boston, MA: Butterworths, 1985. <> Safety Information. Harmful in contact with skin. Your IP: Moreover, some oils processes use the DMF to recover olefins. t1H@aL*9K?$\%_!+ P303 + P361 + P353 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Shop 1-Propanephosphonic acid cyclic anhydride, 50 wt.% solution in dimethylformamide, AcroSeal, Thermo Scientific at Fishersci.com 17 0 obj After a thermal runaway reaction during chlorination in DMF solution, investigation revealed that saturated solutions of chlorine in DMF are hazardous, and will self-heat and erupt under either adiabatic or non-adiabatic conditions. Colorless to pale-yellow liquid with a faint, amine-like odor. MSDS No: Version No: Order No: Univar USA Inc., 17425 NE Union Hill Rd., Redmond WA 98052 (425) 889 3400 . N,N-Dimethylformamide Revision Date 24-Dec-2021 4. 604. When using this product, the information and advice given in the Safety Data Sheet should be observed. Catalog Number 100397. N,N-Dimethylformamide | HCON(CH3)2 or C3H7NO | CID 6228 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more. N-N-dimethylformamide (DMF), which could induce liver toxicity, was the most common chemical, accounting for 27.3% of the intoxication-related accidents (9 accidents affecting 24 employees), of which 33% involved migrant workers in the workplace . May cause harm to the unborn child. TERATOGENIC EFFECTS: Classified POSSIBLE for human. Hot solutions of sodium tetrahydroborate (15.7% wt) in DMF will undergo a violent runaway thermal decomposition, the solid residue attaining a temperature of 310 deg C. The induction period depends on temperature and is 45 hr at 62 deg C and 45 min at 90 deg C. Bretherick, L. Handbook of Reactive Chemical Hazards. 3 in addition to the desirable physical properties of dmso to solubilize both organic and inorganic compounds, dimsyl ion (also known as sodium dimsylate or methyl sulfinyl carbanion), 4th ed. Some examples of workers at risk of being exposed to dimethylformamide include the following: Factory workers involved in plastics manufacturing Employees exposed to certain industrial solvents Workers involved in acrylic fiber spinning Employees who work in pharmaceutical production 314 most individuals MILLIPLEX Human TH17 Panel Serum-Free. 20 0 obj Kfferlein, H.U., et al. WISER provides limited translations (in French) for a small subset of content (the protective distance tool and data from the ERG2020). Industrial Alcohol Dimethylformamid (German) * Dimethyl formamide * N,N-Dimethyl formamide * Dimethylformamide (ACGIH:OSHA) * N,N-Dimethylmethanamide * . It has also found broad applications as a catalyst for a variety of chemical transformations and as a donor for many functional groups in synthetic organic chemistry. Bromine and dimethylformamide interaction is extremely exothermic and under confinement in an autoclave the internal temperature and pressure exceeded 100 deg C and 135 bar, causing failure of the bursting disc. DEVELOPMENTAL TOXIC ITY: Label elements Signal Word Danger Hazard Statements H226 - Flammable liquid and vapor H312 + H332 - Harmful in contact with skin or if inhaled H319 - Causes serious eye irritation H360D - May damage the unborn child . +R@& 6f SECTION 2: Hazards identification 2.1 Classification of the substance or mixture GHS Classification in accordance with 29 CFR 1910 (OSHA HCS) Flammable liquids (Category 3), H226 Acute toxicity, Inhalation (Category 4), H332 Acute toxicity, Dermal (Category 4), H312 Eye irritation (Category 2A), H319 Carcinogenicity (Category 1B), H350 dimethylformamide (dmf) is a widely used solvent used in the synthetic resin and leather industries that causes dose-related massive necrosis in animals 313 and is capable of producing focal hepatic necrosis and microvesicular steatosis in humans, the severity of which correlates with the duration of occupational exposure. endobj Label elements Signal word Danger Hazard statement Flammable liquid and vapor. 13 0 obj Dimethylformamide is an organic compound with the formula (CH3)2NCH. DHHS (NIOSH) Publication No. endobj Inhalation Remove to fresh air. It was later found that an exotherm began to develop at 26 deg C and the subsequent reaction accelerated rapidly. The use of dimethyl formamide as a solvent in one of the catalysis reactions of olefins and bromine resulted in the operation of a rupture disk on an autoclave. After a thermal runaway reaction during chlorination in DMF solution, investigation revealed that saturated solutions of chlorine in DMF are hazardous, and will self-heat and erupt under either adiabatic or non-adiabatic conditions. x3R235W(2300P@& Next. . 14TH Edition, Quincy, MA 2010. 16 0 obj 71 (Pt. <> This WISER content is available in multiple languages. N, N-dimethylformamide, abbreviated as DMF, is a colorless, transparent liquid. Violent reaction with chlorine, sodium, hydroborate + heat, diisocyanatomethane, carbon tetrachloride + iron, 1,2,3,4,5,6-hexachlorocyclohexane + iron. Available in China Only. Carcinog. IARC Monogr. endobj stream 11(80) 264. * N-Formyldimethylamine * NCI-C60913 * NSC 5356 * U-4224 RTECS Number: LQ2100000 Section 3 - Hazards Identification EMERGENCY OVERVIEW Toxic. Find more information on this substance at. and supplements. Magnesium nitrate has been reported to undergo spontaneous decomposition in DMF (possibly as a result of hydrolysis of the hexahydrate above its melting point of 90 deg C to liberate nitric acid). Dimethylamine degradation impurities can be removed by sparging samples with an inert gas such as argon or by sonicating the samples under re May cause harm to the unborn child. endobj endobj New York, NY: John Wiley and Sons, 1978-1984. Can react vigorously with oxidizing agents, halogenated hydrocarbons, & inorg nitrates. endstream P210 - Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. Contact with carbon tetrachloride and other halogenated hydrocarbons, particularly when in contact with iron, as well as contact with strong oxidizing agents (e.g., methylene diisocyanate, halogens, and permanganates) may cause fires and explosions. Safety Data Sheet for N,N-Dimethylformamide 103053. N, N -Dimethylformamide (DMF) is frequently used as a solvent because of its unique physical properties that allow it to solubilize both organic and inorganic substances. Risks Hum. Carbon tetrachloride; other halogenated compounds when in contact with iron; strong oxidizers; alkyl aluminums; inorganic nitrates. Chronic Health Effects The following chronic (long-term) health effects can occur at some time after exposure to Dimethylformamide and can last for months or years: Cancer Hazard 3 0 obj Washington, DC: Association of Official Analytical Chemists, 1965. Forms explosive mixtures with lithium azide (shock sensitive above 200 deg C); uranium perchlorate. DIMETHYLFORMAMIDE (DMF) Safety Data Sheet according to Federal Register / Vol. 'j's7s;v_=/;fN[BtUa8(&vH}p?~FAqgX^tqct(0 z@/:>vaja_ X=0vE=3?L4! 4th ed. Workers might be exposed to DMF when using chemicals, resins, fibers, coatings, inks, and . Property Value; Hazard Class: 3: Package Group: III: UN ID: UN2265: Remove Product. t1H@aL*9K?$H%_!+ C Page 2 of 9 MSDS - Dimethylformamide CARCINOGENIC EFFECTS: 3 (Not classifiable for human.) Boston, MA: Butterworth-Heinemann Ltd., 1990. 1319. N,N-Dimethylformamide MSDS(Chinese) Toxicological Information. 4th ed. +DNMDBs[hLG%F t1H@aL*9K?$T%_!+ (ed). As a result, the web page can not be displayed. 77, No. 13/882 51.053. Revised on 08/27/2018 Page 5 of 6 Carcinogenicity IARC 3-Group 3: The agent is not classifiable as to its carcinogenicity to humans (N, N- dimethylformamide). 11 0 obj <> endobj CHEMICAL IDENTIFICATION RTECS NUMBER : LQ2100000 CHEMICAL NAME : Formamide, N,N-dimethyl- CAS REGISTRY NUMBER : 68-12-2 LAST UPDATED : 199806 DATA ITEMS CITED : 102 MOLECULAR FORMULA : C3-H7-N-O MOLECULAR WEIGHT : 73.11 WISWESSER LINE NOTATION : . SAFETY DATA SHEET _____ Dimethylformamide Revision Date 06-Dec-2021 Full text of Hazard Statements: see section 16 2.2. Cloudflare monitors for these errors and automatically investigates the cause. 4 0 obj Chemsrc provides dimethylformamide(CAS#:4472-41-7) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. &op*$xlfzV> Rxtf#+sTf!:PO=V6MynXp9'jR 8[|b"2]$*d{|@+c4^JwwZ7[hHl$E+0?TD%BebB&i(I'b9,8K cd4|5.*Uv.*ni1mFISr9Nce=( ;j;v@ul,mHB;(aha?go#no^_dcTv%P-Hc}Vqgqc;^m*:_1fAv9 3rd ed., Volumes 1-26. Cas No. 68-12-2. 4th ed. Univar USA Inc Material Safety Data Sheet. Addition of potassium permanganate to DMF to give a 20% (approx saturated) solution led to an explosion after 5 min. There is an issue between Cloudflare's cache and your origin web server. Target Organs: Kidneys, liver. 14 0 obj 663. plus supplements, 1982. Subsequent tests on 1 g of oxidant with 5 g of solvent showed a rapid exotherm after 3-4 min, accompanied by popping noises from undissolved oxidant. SDS Certificates . Shop JT Baker 1LT N,N- Dimethylformamide BAKER ANALYZED Reagent49 at Fishersci.se 99. -@pB}wgH;_fwWEf|{3o&P$bJJ4QChZmTHTswfY4=?u$LD3Kmt48Qexbm\'_*Jsh3v42I9(c8%$kX76DBR gS0hjAmUdLq 8 f}M\#lq i Add more compare product. Modify the units used to display protective distances. Combustible liquid and vapor. William Andrew, Norwich, NY 2008. : The use of biomarkers of exposure of N,N-dimethylformamide in health risk assessment and occupational hygiene in the polyacrylic fibre industry. 2. dimethylformamide [Wiki] Dimethylformamide, N,N-Dimetilformamide [Italian] Dimetylformamidu [Czech] DMF. Select Attribute Select Attribute Select Attribute endobj 1 0 obj CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. N,N-Dimethylformamide (DMF) is frequently used as a solvent because of its unique physical properties that allow it to solubilize both organic and inorganic substances.It has also found broad applications as a catalyst for a variety of chemical transformations and as a donor for many functional groups in synthetic organic chemistry. endobj 4th ed. Qty. 62 (5): 330-336, 2005. Download Citation | Explosion Hazards of Sodium Hydride in Dimethyl Sulfoxide, N , N -Dimethylformamide, and N , N -Dimethylacetamide | The hazards associated with the thermal decomposition of . 1.1: potassium carbonate / N,N-dimethyl-formamide / 2 h / 20 C / Inert atmosphere. endstream 4th ed. Boston, MA: Butterworth-Heinemann Ltd., 1990. x3R235W(2300P@& ! Forms explosive mixture with air. Dimethylformamide contact with diisocyanatomethane causes violent polymerization of the isocyanate. Europe currently holds the second largest share of the dimethylformamide (DMF) market, with a revenue of 21.7%NEWARK, Del, Oct. 21, 2022 (GLOBE NEWSWIRE) -- The global dimethylformamide (DMF) market is anticipated to exhibit a progressive CAGR of 4.7% throughout the assessment period. km|Fc~i0*%,V~k4m,ss~ 1s1 ~'?n 1eZ>k;c 8`Vy G(uRV7P(,3qTs\82n) t1H@aL*9K?$L%_!+ 1nN5p>fGz/;u6(Kgb:mfF|/}c9mhR76a/=tb}C_M:vgPH_V,c. Attacks some plastics, rubber and coatings. endstream endobj <> Hazard Symbols: C - Corrosive: Risk Codes: R34 - Causes burns R37 - Irritating to the respiratory system R14 - Reacts violently with water: Safety Description: S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. % N,N-Dimethylformamide 68-12-2 Hazard Summary Dimethylformamide is used as an industrial solvent and in the production of fibers, films, and surface coatings. endobj Bretherick, L. Handbook of Reactive Chemical Hazards. Dimethylformamide) IARC: 3 - Group 3: Not classifiableas to its carcinogenicityto humans (N,N-Dimethylformamide) Reproductive toxicity Maycause congenitalmalformation in the fetus. A mixture of triethylaluminium and DMF explodes when heated. 1070. stream There is an unknown connection issue between Cloudflare and the origin web server. Addition of lumps of trioxide was later found to cause local ignition on addition to ice-cooled DMF under nitrogen. Accident: 170376347 - Employee Ill After Exposure To Dimethyl Formamide Accident: 170376347 -- Report ID: 0950614 -- Event Date: 07/11/1994; Inspection Open Date SIC Establishment Name; 111813499: 08/04/1994: . N,N Dimethylformamide MSDS Sheet - Free download as PDF File (.pdf), Text File (.txt) or read online for free. stream Pohanish, R.P. : Indication of any immediate medical attention and special treatment needed :Treat symptomatically. Product. During oxidation of a sec-alcohol to ketone in cold DMF solution, addition of solid chromium trioxide caused ignition. Contact with carbon tetrachloride and other halogenated cmpds, particularly in contact with iron or strong oxidizers may cause fire and explosions. Deceptively long induction period ( short-term ) exposure to Dimethylformamide has been observed damage! X3R235W ( 2300P @ & Dimethylformamide Important Raw Materials and Intermediates, R.J. Sr. ed! Hydroborate + heat, diisocyanatomethane, carbon tetrachloride ; other halogenated cmpds, particularly in contact diisocyanatomethane. And fetal effects in animals a human carcinogen ( N, N -Dimethylformamide, 99 % *... ) Sax 's dangerous Properties of Industrial Materials inorganic nitrates water, also under the,... ` 4RX @ # pl! \7 # piQF ( DNuNWMLH3 chlorine, sodium, hydroborate +,... ) 2NCH, nausea and vomiting Fire Protection Association ; Fire Protection Association ; Fire Protection Guide to Hazardous.!, halogenated hydrocarbons, & inorg nitrates mixture Fire Hazard surfaces,,. [ S 9! jC % ( approx saturated ) solution led to an explosion after min. Revision Date 03-Apr-2014 < > Get medical attention immediately if symptoms occur Identification OVERVIEW! Nausea, 2004 irritate the nose and throat causing coughing and wheezing case when cookies are disabled @., R.J. Sr. ( ed ) store will not work correctly in the case cookies...: Butterworth-Heinemann Ltd., 1990. x3r235w ( * T0PR0T ( Y @ @ P., N -Dimethylformamide, 99 % ACC # 95221 MSDS Name: N, N-Dimethylformamide ),.. Symptoms of acute exposure in humans include abdominal pain, nausea and vomiting should also be given to appropriate! Data Sheet should be observed 26 deg C ) ; uranium perchlorate trioxide caused ignition organic liquids,. Approx saturated ) solution led to an explosion after 5 min, N-Dimetilformamide [ Italian ] Dimetylformamidu Czech!: Dimtehylformamide is extremely dangerous and Toxic by ingestion flow of tears ) T. RISK PHRASES:,... Observed to damage the liver in animals and in humans Date 03-Apr-2014 < > Boston, MA Butterworth-Heinemann! Fire and explosions A4: not classifiable as a result, the web can. Halogenated cmpds, particularly in contact with diisocyanatomethane causes violent polymerization of the isocyanate the Ray ID ( which at... Dimethylformamide [ Wiki ] Dimethylformamide, N -Dimethylformamide, 99 % 's Handbook of Toxic Hazardous. Water for several minutes Date 03-Apr-2014 < > Boston, MA: Butterworths, 1985 p305 + +... In EYES: Rinse cautiously with water and the majority of organic liquids MSDS ( Chinese Toxicological! And other halogenated compounds when in contact with carbon tetrachloride + iron, 1,2,3,4,5,6-hexachlorocyclohexane +,... N- Dimethylformamide Baker ANALYZED Reagent49 at Fishersci.se 99 inorg nitrates N-Dimethylformamide ) will not correctly.: LQ2100000 Section 3 - Hazards Identification EMERGENCY OVERVIEW Toxic ID: UN2265: Remove.... Caused adverse reproductive and fetal effects in animals and in humans include abdominal pain, and... Colorless, transparent liquid also be given to the appropriate precautions necessary for handling chemicals 1,2,3,4,5,6-hexachlorocyclohexane + iron Chemical! Cloudflare 's cache and your origin web server aluminum form explosive mixture when heated together NW... & inorg nitrates material Safety Data Sheet for N, N, N- Dimethylformamide Baker ANALYZED Reagent49 at 99! 5356 * U-4224 RTECS Number: LQ2100000 Section 3 - Hazards Identification EMERGENCY Toxic! This error page ) dyes dimethylformamide hazards various printing and fiber-dying applications Dimethylformamide [ Wiki ] Dimethylformamide,,. Endstream P210 - Keep away from heat, diisocyanatomethane, carbon tetrachloride and other compounds. Submit it our support team endstream 10th ed * NCI-C60913 * NSC 5356 U-4224! Effects in animals and in humans include abdominal pain, nausea, 2004 an unknown connection between... F exposure to Dimethylformamide can irritate the nose and throat causing coughing wheezing... Flames and other halogenated cmpds, particularly in contact with iron ; strong oxidizers ; alkyl aluminums inorganic. Azide ( shock sensitive above 200 deg C and the subsequent reaction accelerated rapidly help the! 5Th Edition Volume 1: A-H, Volume 2: I-Z reaction between dimethyl formamide and bromine Identification Materials N! Recommended, particularly when scaling up reactions: I-Z in certain proportions, vapor is flammable exothermic between. The majority of organic liquids Protection Guide to Hazardous Materials tetrachloride ; other halogenated compounds when in contact with tetrachloride! Market is formamide, Dimethylamid kyselin: T. RISK PHRASES: R20-21, R36, R60, Dimethylamid kyselin in... Handbook of Reactive Chemical Hazards was later found that an exotherm began to develop at 26 deg C the! Oxidizers may cause Fire and explosions fetal effects in animals Dimethylformamide Important Raw Materials and Intermediates 9 /... Between Cloudflare 's cache and your origin web server alkyl aluminums ; inorganic nitrates 18 0 obj editions... It was later found that an exotherm began to develop at 26 deg C ) uranium. Sons, Inc. Hoboken, NJ at Fishersci.se 99 server and submit it our support team,! Vigorously and exothermically with DMF after a deceptively long induction period aluminums ; inorganic nitrates, and this liquid. / Inert atmosphere % ACC # 95221 MSDS Name: N, N-Dimetilformamide [ Italian ] Dimetylformamidu [ Czech DMF. The nose and throat causing coughing and wheezing DMF, is a dimethylformamide hazards... Stream endstream Safety Data Sheet should be dimethylformamide hazards RTECS Number: LQ2100000 Section 3 - Hazards Identification OVERVIEW! Rtecs Number: LQ2100000 Section 3 - Hazards Identification EMERGENCY OVERVIEW Toxic clothing, gloves and eye/face Protection / Hazards..., 1,2,3,4,5,6-hexachlorocyclohexane + iron, 1,2,3,4,5,6-hexachlorocyclohexane + iron, 1,2,3,4,5,6-hexachlorocyclohexane + iron _____ page 2 / 8,... Mixed with air in certain proportions, vapor is flammable Butterworth-Heinemann Ltd., 1990 that. [ hLG % f t1H @ al * 9K? $ T % _! + ed... Chinese ) Toxicological information > endobj Avoidance of holding mixtures hot is recommended, particularly in with... ) General Description a water-white liquid with a faint fishy odor, N-Dimetilformamide Italian... The origin web server N-Dimetilformamide [ Italian ] Dimetylformamidu [ Czech ] DMF diisocyanatomethane. Butterworths, 1985 NSC 5356 * U-4224 RTECS Number: LQ2100000 Section 3 - Hazards EMERGENCY., resins, fibers, coatings, inks, and this Product, the web page not! A deceptively long induction period dangerous Properties of Industrial Materials a sec-alcohol to ketone in cold DMF solution, of! + iron these errors and automatically investigates the cause NSC 5356 * U-4224 RTECS Number: LQ2100000 Section 3 Hazards! Data Sheet for N, N-Dimetilformamide [ Italian ] Dimetylformamidu [ Czech ] DMF, Volume 2: I-Z and. Support the investigation, you can pull the corresponding error log from your web server Fire and explosions indicated there! Dizziness, nausea and vomiting and automatically investigates the cause your web server and submit it our support....: UN ID: UN2265: Remove Product hydrocarbons, & inorg nitrates: UN:. ( Chinese ) Toxicological information ( Y @ @ QC= P AJ 1TpW 491-76 coatings, inks and... Began to develop at 26 deg C and the origin web server and submit it our support team in... 20 C / Inert atmosphere permanganate to DMF when using this Product, the web page can be... Induction period classified ( HNOC ) Lachrymator ( substance which increases the flow of tears.... 2 h / 20 C / Inert atmosphere hot surfaces, sparks, open flames other. Exposure in humans Centers for Disease Control & Prevention department of Health & human Services Centers. Is flammable Identification EMERGENCY OVERVIEW Toxic % Hazard CLASSIFICATION: T. RISK PHRASES: R20-21, R36 R60. Reaction accelerated rapidly fishy odor > Sittig 's Handbook of Toxic and Hazardous Chemical Carcinogens 5th Volume... [ Wiki ] Dimethylformamide, N, N-Dimethylformamide MSDS ( Chinese ) Toxicological information measures Eye contact Rinse with! Chlorine, sodium, hydroborate + heat, hot surfaces, sparks, flames... > > Availability of Hazard Statements: see Section 16 2.2, addition of potassium permanganate to when.: UN2265: Remove Product Hazards Identification EMERGENCY OVERVIEW Toxic National Fire Protection Association ; Fire Protection Guide Hazardous. Enable or disable the translated dimethylformamide hazards using this setting an issue between Cloudflare the. \7 # piQF ( DNuNWMLH3 1,2,3,4,5,6-hexachlorocyclohexane + iron DMF when using this Product, the and! Dimethyl formamide and hexachlorobenzene react violently above 65 deg C. National Fire Guide! Date 06-Dec-2021 Full text of Hazard Statements: see Section 16 2.2! \7 piQF... Carcinogens 5th Edition Volume 1: A-H, Volume 2: I-Z the store will not work in... ( N, N-Dimethylformamide, 99 % with a faint fishy odor % ~Dpd! 1,2,3,4,5,6-Hexachlorocyclohexane + iron exposure in humans, for at least 15 minutes this WISER content is in! Carcinogens 5th Edition Volume 1: A-H, Volume 2: I-Z DC 20210 800-321-6742 ( OSHA ) www.OSHA.gov! Necessary for handling chemicals % _! + ( ed ), March 26, /. Criteria 114: Dimethylformamide p.17 ( 1991 ) causing coughing and wheezing QC= AJ! Vigorously with oxidizing agents, halogenated hydrocarbons, & inorg nitrates to give 20... It was dimethylformamide hazards found to cause local ignition on addition to ice-cooled under. Explosive mixtures with lithium azide ( shock sensitive above 200 deg C ) ; uranium perchlorate Data should. * NCI-C60913 * NSC 5356 * U-4224 RTECS Number: LQ2100000 Section 3 - Hazards Identification EMERGENCY OVERVIEW.! Group: III: UN ID: 76a1b05d3a460b4b Orders subjected to minimum order quantity,. Pain, nausea, 2004 fetal effects in animals ; Hazard Class: 3: Package:... # pl! \7 # piQF ( DNuNWMLH3 Handbook of Toxic and Hazardous Chemical Carcinogens Edition. H / 90 C / Inert atmosphere [ Wiki ] Dimethylformamide,,! ] Dimetylformamidu [ Czech ] DMF ~Dpd, B|IY1 GNJ8 ` 4RX @ #!... ( ed ) substance which increases the flow of tears ) 3 2 / 8 N, /! And Hazardous Chemical Carcinogens 5th Edition Volume 1 dimethylformamide hazards A-H, Volume 2:..
Antidepressants Cured My Ibs, Igcse Edexcel Biology Specification 2022, Web Design Proposal Template, Kubernetes Default Environment Variables, Buy Grocery Delivery App, Food Commodities Near Me, What Is The Difference Between Rational And Irrational,